Manufacturing of CAR-T Cell Therapies
Overview
This 2.5-day course is delivered onsite at the NIBRT facility.
An understanding of the manufacturing processes of cell therapies is essential for ensuring they are produced safely and effectively, and that they can gain regulatory approval. Held at NIBRT’s cutting-edge Advanced Therapy training facility, the course offers practical, hands-on experience with the latest CAR-T manufacturing technologies, including example process flows. NIBRT equipment for CAR-T cell processing includes technologies for isolation, expansion, scale-up, harvest, and cryopreservation for CAR-T Cell Therapies. These technologies all represent the latest approached to GMP manufacturing of this modality.
Accompanying lectures will enhance understanding of the technologies, processes, and regulatory considerations specific to ATMP manufacturing.
Key topics covered
- CAR-T Cell Engineering and Production
- Regulatory and Logistical Challenges
- T Cell Collection (Apheresis) and Isolation
- Viral and Non-Viral Methods for Gene Modification
- CAR Design and Transduction Techniques (Lentiviral, Retroviral Vectors)
- Expansion and Cryopreservation of CAR-T Cells
- Quality Control in CAR-T Manufacturing, including Rapid Micro Methods
Who should attend
Operators will gain valuable hands-on experience with practical exercises. The course’s interactive approach ensures that they can confidently apply these skills in real-world settings, improving their proficiency and troubleshooting capabilities.
Scientists and senior management will benefit from the visualisation of complex theories and processes, bridging the gap between technical knowledge and operational practices. By seeing the theory in action, they will gain a deeper understanding of critical systems, enabling them to make more informed decisions and optimise their departments’ performance.
What do Attendees Obtain on Completion?
A competency-based assessment will be taken at the end of the course. Attendees will receive a certificate of attendance.
Register
Course Format
Onsite Training at NIBRT
Onsite Training at NIBRT
- 2.5 full days onsite training at NIBRT facility
Course on request – please contact Training@nibrt.ie
