NIBRT Launch New Dedicated Advanced Therapies Facility
NIBRT is delighted to announce the successful launch of our advanced therapies extension, a facility dedicated to advancing research and training in Advanced Therapy Medicinal Products (ATMPs), including Cell and Gene Therapy. With a €21 million investment from the IDA Ireland and the Government of Ireland, this state-of-the-art extension features 1,800m2 of cutting-edge space, housing seven specialised laboratories for ATMP therapy research and two advanced training suites. This marks a pivotal moment as NIBRT takes its place at the forefront of ATMP innovation, driving excellence in research and training.
Advanced Therapies Research at NIBRT
The new extension includes seven new laboratories dedicated to research focused on the manufacture and characterisation of advanced therapies. NIBRT's current research interests and capabilities in this space include:
- CONCEPT a core facility for early-stage biotherapy development CONCEPT | National Synthetic Biology and Cell Line Development Facility (concept-nibrt.ie)
- Human (HEK293) and insect (SF9) production systems for AAV and LV gene therapy vector production
- Next generation sequencing approaches to identifying mispackaging of viral genomes
- Genetic engineering approaches to enhancing gene therapy vector yield and activity
- Novel MS-based analytical methods for viral capsid and genome characterisation
- Epi-transcriptomic modification to enhance RNA characteristics as a therapeutic modality
- Chemical modification of RNA to improve vaccine stability
NIBRT is now actively recruiting and developing research teams focused on the characterisation and manufacture of advanced therapies. If you are interested in current opportunities in this space please contact careers@nibrt.ie
Advanced Therapies Training at NIBRT
NIBRT’s advanced therapies training curriculum encompass a blended approach of online, classroom and practical sessions related to the manufacturing of cell therapies, gene therapies and vaccines. The curriculum is developing rapidly and current training programmes include:
NIBRT Online Academy
- Introduction to Cell Therapy
- Introduction to Gene Therapy
- Viral Vector Manufacturing, a suite of five online courses covering upstream scale up, downstream processing and analytics of viral vectors used in gene therapy
- Free webinars on Vaccine Manufacturing
Practical courses
A key focus is on the delivery of competency-based, hands-on practical sessions utilising best-in-class equipment and facilities to our clients. Current courses available include:
- Manufacturing of Stem Cell Therapies
- Manufacturing of CAR-T Cell Therapies
- Introduction to mRNA Manufacturing Operations
- Introduction to ATMP Manufacturing
- Introduction to Gene Therapy Manufacturing
- Fundamentals of Vaccine Manufacture
- Introduction to Cell Therapy Manufacturing
NIBRT specialises in designing, developing, and delivering customised training programmes to meet the requirements of industrial clients. All advanced therapies short courses can be tailored to suit clients individual requirements.
Sample Advanced Therapies Manufacturing Curriculum
Higher Education Programmes in Partnership with ATU Sligo
MSc in ATMP Cell Manufacturing
MSc in ATMP Technology and Manufacturing
For further information of how NIBRT can support your advanced therapies training requirements, please contact training@nibrt.ie
Cell & Gene Therapy (CGT) Forum
In 2018, NIBRT working with a broad coalition of stakeholders established the Cell & Gene Therapy Forum (CGT Forum) in order to address the opportunity for Ireland to capitalise on the burgeoning therapeutic and commercial interest in advanced therapies. For further information on CGT Forum contact Prof Niall Barron niall.barron@nibrt.ie.
NIBRT working closely with the CGT Forum recently launched a website (www.atmp.ie) that will act as a central portal for information on the advanced therapies industry in Ireland including latest news, an extensive database and training and investment opportunities.
